BPC 157 is a stable, 15-amino acid peptide fragment designated as PL 14736.It is derived from a larger osteogenic protein known as Body Protection Compound (BPC), which is naturally produced in the stomach.
In research settings, BPC 157 is distinguished by its ability to survive gastric enzymes and remain active without a carrier.Its primary mechanism of action involves the stimulation of angiogenesis (the formation of new blood vessels) via the activation of the VEGFR2 pathway.This increased blood flow is believed to be the driver behind its regenerative effects on damaged soft tissue, bone, and the intestinal lining.
Furthermore, BPC 157 is observed to influence the release of nitric oxide (NO), offering tissue protection (cytoprotection) against damage from toxins, NSAIDs, and stress.It is a primary subject of interest in studies involving inflammatory bowel disease (IBD), tendon-to-bone healing, and the repair of the gut-brain axis.