Ipamorelin 10mg

Ipamorelin 10mg

£129.00

Selective Third-Generation Growth Hormone Secretagogue        

Executive Overview

Ipamorelin is a synthetic pentapeptide recognized as one of the most chemically advanced and selective agents in the Growth Hormone Secretagogue (GHS) family. Composed of the specific sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2, it represents a “third-generation” refinement in peptide engineering.

While it shares the core objective of stimulating growth hormone (GH) release, Ipamorelin is distinguished by its extreme receptor specificity. It is designed to maximize the GH pulse while eliminating the undesirable side effects associated with earlier analogues.

Advanced Mechanism of Action

Ipamorelin functions as a potent mimetic of the endogenous ligand ghrelin. It selectively binds to the Growth Hormone Secretagogue Receptor (GHSR-1a) located in the anterior pituitary gland and the hypothalamus.

Key Differentiators in Research:

  • Unrivaled Selectivity: Unlike GHRP-2 or GHRP-6, Ipamorelin’s binding is highly targeted. Even at elevated research doses, it does not cross-react with receptors that trigger the release of ACTH (Adrenocorticotropic hormone), Cortisol, or Prolactin.

  • Physiological Pulse Mimicry: It promotes a robust, pulsatile release of GH that closely resembles natural biological rhythms, rather than causing a sustained, unnatural “bleed” of hormone levels.

  • Ghrelin-Like without the Hunger: While it activates the ghrelin receptor, Ipamorelin is noted for having a negligible effect on appetite stimulation (orexigenic effect), making it a precise tool for studying GH in isolation from metabolic/hunger pathways.

Chemical & Physical Specifications

Property Specification
Product Name Ipamorelin
Molecular Formula
Molecular Weight 711.85 g/mol
CAS Number 170851-70-4
Purity (HPLC) ≥98.0%
Physical Form Sterile, white lyophilized crystalline powder
Sequence ––––––––

Handling and Stability Protocols

To ensure the molecular integrity of the pentapeptide chain:

  • Storage (Lyophilized): Long-term stability is best maintained at -20°C.

  • Storage (Reconstituted): Once dissolved in Bacteriostatic Water or Sterile Saline, the solution must be stored at 2°C to 8°C.

  • Sensitivity: Avoid exposing the reconstituted peptide to direct sunlight, high temperatures, or vigorous mechanical agitation (shaking), which can lead to denaturation of the peptide bonds.

Strict Research Disclaimer

FOR RESEARCH USE ONLY (RUO): This product is synthesized and supplied exclusively for in vitro laboratory analysis and scientific research. It is not a medical grade product and is strictly prohibited for human or veterinary consumption, therapeutic application, or clinical diagnostics.

ENQUIRY!
Category

Product Enquiry