£149.00
Overview
GHRP-6 is a pioneering first-generation hexapeptide composed of a specialized six-amino acid sequence: His-D-Trp-Ala-Trp-D-Phe-Lys-NH2. It is recognized as a cornerstone in the study of growth hormone secretagogues (GHS) and remains one of the most extensively profiled peptides in endocrine research.
Unlike GHRH-based peptides, GHRP-6 operates via the ghrelin pathway, providing researchers with a unique tool to study the intersection of growth hormone production, metabolic signaling, and appetite regulation.
Mechanism of Action
GHRP-6 functions as a high-affinity synthetic agonist of the Growth Hormone Secretagogue Receptor (GHSR-1a). Its biological impact is characterized by a triple-action pathway:
Pulsatile GH Release: By targeting GHSR-1a receptors in the anterior pituitary, it triggers a rapid, significant burst of endogenous growth hormone.
Ghrelin Mimicry & Orexigenic Effect: Because it mimics ghrelin, GHRP-6 is a potent simulator of hunger. It is specifically researched for its role in increasing gastric motility and modulating energy balance via hypothalamic signaling.
Somatostatin Antagonism: It enhances the total GH output by suppressing Somatostatin (Growth Hormone-Inhibiting Hormone), effectively removing the natural inhibitory “brake” on the pituitary gland.
Chemical & Physical Specifications
| Property | Specification |
| Product Identifier | GHRP-6 |
| Total Quantity | 10 mg |
| Molecular Formula | C46H56N12O6 |
| Molecular Weight | 873.0 g/mol |
| Amino Acid Sequence | His–D–Trp–Ala–Trp–D–Phe–Lys–NH2 |
| CAS Number | 87616-84-0 |
| Purity (HPLC) | ≥98% |
Stability & Handling Protocols
To ensure the preservation of the hexapeptide’s potency and structural integrity:
Physical Form: Sterile, white lyophilized crystalline powder.
Short-Term Storage: 2°C to 8°C (Refrigerated).
Long-Term Storage: -20°C (Frozen) is recommended to prevent deamidation.
Reconstitution: Must be dissolved in Bacteriostatic Water or Sterile Saline prior to use. Avoid vigorous agitation once the peptide is in solution.
Strict Research Disclaimer
WARNING: This product is synthesized and supplied strictly for Laboratory Research and Analytical Use Only. It is not intended for human or veterinary consumption, medical diagnosis, or therapeutic application. All handling must be conducted by qualified personnel in a controlled research environment.
